1. Saraiva, C.; Paiva, J.; Santos, T.; Ferreira, L.; Bernardino, L., MicroRNA-124 loaded nanoparticles enhance brain repair in Parkinson’s disease. J Controlled Release 2016.
  1. Saraiva, C.*; Praça, C.*; Ferreira, R.; Santos, T.; Ferreira, L.+; Bernardino, L.+, Nanoparticle-mediated brain drug delivery: Overcoming blood–brain barrier to treat neurodegenerative diseases. J Controlled Release 2016, 23534-47.
  1. Tenreiro, M. M.*; Ferreira, R.*; Bernardino, L.; Brito, M. A., Cellular response of the blood-brain barrier to injury: Potential biomarkers and therapeutic targets for brain regeneration. Neurobiol Dis 2016.
  1. Rocha, S. M.; Saraiva, T.; Cristóvão, A. C.; Ferreira, R.; Santos, T.; Esteves, M.; Saraiva, C.; Je, G.; Cortes, L.; Valero, J., et al., Histamine induces microglia activation and dopaminergic neuronal toxicity via H1 receptor activation. Journal of Neuroinflammation 2016, 13(1), 1-16.
  1. Santos, T.*; Boto, C.*; Saraiva, C. M.; Bernardino, L.+; Ferreira, L.+, Nanomedicine Approaches to Modulate Neural Stem Cells in Brain Repair. Trends Biotechnol 2016.
  1. Ferreira, R.+; Fonseca, M. C.; Santos, T.; Sargento-Freitas, J.; Tjeng, R.; Paiva, F.; Castelo-Branco, M.; Ferreira, L. S.; Bernardino, L.+, Retinoic acid-loaded polymeric nanoparticles enhance vascular regulation of neural stem cell survival and differentiation after ischaemia. Nanoscale 2016, 8(15), 8126-8137.
  1. Ferreira, R.+; Bernardino, L.+, Dual role of microglia in health and disease: pushing the balance toward repair. Front Cell Neurosci 2015, 951.
  1. Esteves, M.; Cristovao, A. C.; Saraiva, T.; Rocha, S. M.; Baltazar, G.; Ferreira, L.; Bernardino, L., Retinoic acid-loaded polymeric nanoparticles induce neuroprotection in a mouse model for Parkinson’s disease. Front Aging Neurosci 2015, 720.
  1. Serpa, A.; Pinto, I.; Bernardino, L.; Cascalheira, J. F., Combined neuroprotective action of adenosine A1 and cannabinoid CB1 receptors against NMDA-induced excitotoxicity in the hippocampus. Neurochem Int 2015, 87106-9.
  1. Eiriz, M. F.; Valero, J.; Malva, J. O.; Bernardino, L., New insights into the role of histamine in subventricular zone-olfactory bulb neurogenesis. Front Neurosci 2014, 8142.
  1. Xapelli, S.; Agasse, F.; Grade, S.; Bernardino, L.; Ribeiro, F. F.; Schitine, C. S.; Heimann, A. S.; Ferro, E. S.; Sebastiao, A. M.; De Melo Reis, R. A., et al., Modulation of subventricular zone oligodendrogenesis: a role for hemopressin? Front Cell Neurosci 2014, 859.
  1. Santos, T.; Fang, X.; Chen, M. T.; Wang, W.; Ferreira, R.; Jhaveri, N.; Gundersen, M.; Zhou, C.; Pagnini, P.; Hofman, F. M., et al., Sequential administration of carbon nanotubes and near-infrared radiation for the treatment of gliomas. Front Oncol 2014, 4180.
  1. Rocha, S. M.; Pires, J.; Esteves, M.; Graca, B.; Bernardino, L., Histamine: a new immunomodulatory player in the neuron-glia crosstalk. Front Cell Neurosci 2014, 8120.
  1. Ferreira, R.; Santos, T.; Amar, A.; Tahara, S. M.; Chen, T. C.; Giannotta, S. L.; Hofman, F. M., MicroRNA-18a improves human cerebral arteriovenous malformation endothelial cell function. Stroke 2014, 45(1), 293-7.
  1. Ferreira, R.; Santos, T.; Amar, A.; Gong, A.; Chen, T. C.; Tahara, S. M.; Giannotta, S. L.; Hofman, F. M., Argonaute-2 promotes miR-18a entry in human brain endothelial cells. J Am Heart Assoc 2014, 3(3), e000968.
  1. Xapelli, S.; Agasse, F.; Sarda-Arroyo, L.; Bernardino, L.; Santos, T.; Ribeiro, F. F.; Valero, J.; Braganca, J.; Schitine, C.; de Melo Reis, R. A., et al., Activation of Type 1 Cannabinoid Receptor (CB1R) Promotes Neurogenesis in Murine Subventricular Zone Cell Cultures. PLoS ONE 2013, 8(5), e63529.
  1. Grade, S.; Bernardino, L.; Malva, J. O., Oligodendrogenesis from neural stem cells: perspectives for remyelinating strategies. Int J Dev Neurosci 2013, 31(7), 692-700.
  1. Agasse, F.; Xapelli, S.; Coronas, V.; Christiansen, S. H.; Rosa, A. I.; Sarda-Arroyo, L.; Santos, T.; Ferreira, R.; Schitine, C.; Harnois, T., et al., Galanin promotes neuronal differentiation in murine subventricular zone cell cultures. Stem Cells Dev 2013, 22(11), 1693-708.
  1. Grade, S.; Agasse, F.; Bernardino, L.; Malva, J. O., Functional identification of neural stem cell-derived oligodendrocytes. Methods Mol Biol 2012, 879165-78.
  1. Ferreira, R.; Santos, T.; Goncalves, J.; Baltazar, G.; Ferreira, L.; Agasse, F.; Bernardino, L., Histamine modulates microglia function. J Neuroinflammation 2012, 990.
  1. Ferreira, R.; Santos, T.; Cortes, L.; Cochaud, S.; Agasse, F.; Silva, A. P.; Xapelli, S.; Malva, J. O., Neuropeptide Y inhibits interleukin-1 beta-induced microglia motility. J Neurochem 2012, 120(1), 93-105.
  1. Bernardino, L.*; Eiriz, M. F.*; Santos, T.; Xapelli, S.; Grade, S.; Rosa, A. I.; Cortes, L.; Ferreira, R.; Bragança, J.; Agasse, F., et al., Histamine Stimulates Neurogenesis in the Rodent Subventricular Zone. Stem Cells 2012, 30(4), 773-784.
  1. Baptista, S.; Bento, A. R.; Goncalves, J.; Bernardino, L.; Summavielle, T.; Lobo, A.; Fontes-Ribeiro, C.; Malva, J. O.; Agasse, F.; Silva, A. P., Neuropeptide Y promotes neurogenesis and protection against methamphetamine-induced toxicity in mouse dentate gyrus-derived neurosphere cultures. Neuropharmacology 2012, 62(7), 2413-23.
  1. Santos, T.; Ferreira, R.; Maia, J.; Agasse, F.; Xapelli, S.; Cortes, L.; Bragança, J.; Malva, J. O.; Ferreira, L.; Bernardino, L., Polymeric Nanoparticles to Control the Differentiation of Neural Stem Cells in the Subventricular Zone of the Brain. ACS Nano 2012, 6(12), 10463-10474.
  1. Santos, T.; Maia, J.; Agasse, F.; Xapelli, S.; Ferreira, L.; Bernardino, L., Nanomedicine Boosts Neurogenesis: New Strategies for Brain Repair. Integr Biol 2012, 4(9), 973-981.
  1. Ferreira, R.; Santos, T.; Viegas, M.; Cortes, L.; Bernardino, L.; Vieira, O. V.; Malva, J. O., Neuropeptide Y inhibits interleukin-1beta-induced phagocytosis by microglial cells. J Neuroinflammation 2011, 8169.
  1. Maia, J.*; Santos, T.*; Aday, S.; Agasse, F.; Cortes, L.; Malva, J. O.; Bernardino, L.+; Ferreira, L.+, Controlling the Neuronal Differentiation of Stem Cells by the Intracellular Delivery of Retinoic Acid-Loaded Nanoparticles. ACS Nano 2011, 5(1), 97-106.
  1. Eiriz, M. F.; Grade, S.; Rosa, A.; Xapelli, S.; Bernardino, L.; Agasse, F.; Malva, J. O., Functional evaluation of neural stem cell differentiation by single cell calcium imaging. Curr Stem Cell Res Ther 2011, 6(3), 288-96.
  1. Ferreira, R.; Xapelli, S.; Santos, T.; Silva, A. P.; Cristovao, A.; Cortes, L.; Malva, J. O., Neuropeptide Y modulation of interleukin-1β (IL-1beta)-induced nitric oxide production in microglia. J Biol Chem 2010, 285(53), 41921-34.
  1. Grade, S.; Agasse, F.; Bernardino, L.; Silva, C. G.; Cortes, L.; Malva, J. O., Functional identification of neural stem cell-derived oligodendrocytes by means of calcium transients elicited by thrombin. Rejuvenation Res 2010, 13(1), 27-37.
  1. Rosa, A. I.; Goncalves, J.; Cortes, L.; Bernardino, L.; Malva, J. O.; Agasse, F., The angiogenic factor angiopoietin-1 is a proneurogenic peptide on subventricular zone stem/progenitor cells. J Neurosci 2010, 30(13), 4573-84.
  1. Agasse, F.; Bernardino, L.; Kristiansen, H.; Christiansen, S. H.; Ferreira, R.; Silva, B.; Grade, S.; Woldbye, D. P. D.; Malva, J. O., Neuropeptide Y Promotes Neurogenesis in Murine Subventricular Zone. Stem Cells 2008, 26(6), 1636-1645.
  1. Agasse, F.; Bernardino, L.; Silva, B.; Ferreira, R.; Grade, S.; Malva, J. O., Response to Histamine Allows the Functional Identification of Neuronal Progenitors, Neurons, Astrocytes, and Immature Cells in Subventricular Zone Cell Cultures. Rejuvenation Res 2008, 11(1), 187-200.
  1. Bernardino, L.; Agasse, F.; Silva, B.; Ferreira, R.; Grade, S.; Malva, J. O., Tumor Necrosis Factor-alpha Modulates Survival, Proliferation, and Neuronal Differentiation in Neonatal Subventricular Zone Cell Cultures. Stem Cells 2008, 26(9), 2361-2371.
  1. Xapelli, S.; Bernardino, L.; Ferreira, R.; Grade, S.; Silva, A. P.; Salgado, J. R.; Cavadas, C.; Grouzmann, E.; Poulsen, F. R.; Jakobsen, B., et al., Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: a role for microglia. Eur J Neurosci 2008, 27(8), 2089-102.
  1. Bernardino, L.; Balosso, S.; Ravizza, T.; Marchi, N.; Ku, G.; Randle, J. C.; Malva, J. O.; Vezzani, A., Inflammatory events in hippocampal slice cultures prime neuronal susceptibility to excitotoxic injury: a crucial role of P2X7 receptor-mediated IL-1beta release. J Neurochem 2008, 106(1), 271-80.
  1. Ravizza, T.; Lucas, S. M.; Balosso, S.; Bernardino, L.; Ku, G.; Noe, F.; Malva, J.; Randle, J. C.; Allan, S.; Vezzani, A., Inactivation of caspase-1 in rodent brain: a novel anticonvulsive strategy. Epilepsia 2006, 47(7), 1160-8.
  1. Bernardino, L.; Xapelli, S.; Silva, A. P.; Jakobsen, B.; Poulsen, F. R.; Oliveira, C. R.; Vezzani, A.; Malva, J. O.; Zimmer, J., Modulator effects of interleukin-1beta and tumor necrosis factor-alpha on AMPA-induced excitotoxicity in mouse organotypic hippocampal slice cultures. J Neurosci 2005, 25(29), 6734-44.
  1. Bernardino, L.; Ferreira, R.; Cristovao, A. J.; Sales, F.; Malva, J. O., Inflammation and neurogenesis in temporal lobe epilepsy. Curr Drug Targets CNS Neurol Disord 2005, 4(4), 349-60.

*both authors contributed equally;   +co-corresponding authors


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